This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The Minnesota Children's Museum, in collaboration with the American Library Association will develop a project to engage children ages two through seven years old and their parents in exploring mathematics through hands-on, book-based math activities in libraries and children's museums across the country. The main elements of the project are: 1. A 1200 square foot exhibit at the Minnesota Children's Museum; 2. A traveling exhibit to ten children's museums over a six month period; 3. Five smaller versions of the exhibit will travel to 75 libraries sponsored by the American Library Association. Each library that apply for the exhibit must present a plan in which 50 percent of their exhibit audience will be children and families of the under-represented, lower income groups, and racial and/or ethnic groups. 4. Programs and materials will be designed to provide parents with the means to actively participate in their children's math education. The collaboration of the Minnesota Children's Museum and the American Library Association draws together two organizations whose natural constituencies are parents with young children. Project 1,2,3 is designed to be national in scope and creates multiple formats within which families can enjoy exploring math. Its goals and objectives reflect four messages: start early, math is everywhere, parental involvement and get into books. The project Principal Investigator (PI) Ms. Jeanne W. Vergeront received her Bachelor of Arts and Masters of Science in Child and Family Studies and Environmental Design, respectively from the University of Wisconsin, Madison. Currently, she serves as the Vice President, Educational Projects at the Minnesota Children's Museum in St. Paul, Minnesota.
The New Mexico Museum of Natural History and Science proposed to develop an outreach science and mathematics program with a parent involvement and teacher enhancement professional development component. The goals of the project are as follows: (1) to involve parents in their children's education; (2) to promote a positive attitude on behalf of parents and students toward science and mathematics; (3) to increase teachers' level of comfort in teaching science; and (4) to enhance teacher's confidence in the hands-on approach as an effective method for teaching science. The objectives for the parent component of this project are: acquaint parents with the national and state science education goals and standards; introduce parents to activities that can be done at home with children; and provide families with materials and activity sheets that can be used at home. The objectives for the teacher component of this project are: (1) to provide teachers with opportunities for increased communication with parents about science literacy for children; (2) provide professional development for teachers on the use of hands-on science activities in the classroom; and (3) to providing bilingual activity guides and kits containing materials to encourage science learning. The methods for implementing this project will be varied according to the needs of the target audiences. Parents and children will be engaged through parent workshops and multi-aged children's activities conducted at the museum by experienced science educators. The professional development for teachers' component of this project will include an extensive summer workshop, on-going training/ planning sessions during the school calendar year and session on the uses of the bilingual teaching manuals. The cost sharing for this NSF award is 46.7% of the total project cost.
The Museum of Science in Boston will develop exhibits and programs for visitors to use models as tools for understanding the world around them. It is the 4th stage of a six-part, long-range vision and plan that focuses on comprehending science as a way of thinking and doing. "Making Models" will serve over one million visitors per year, mostly families and school groups. The models to be featured include physical, biological, conceptual, mathematical, and computer simulation models. Four (4) specific science inquiry skills will be stressed, which are associated with making and using models: recognition of similarities, assessment of limitations, communication of ideas, and the creation of one's own models for developing personal understanding and appreciation of the world in which we live. In tandem with this new exhibit, some current exhibits and programs will be modified to meet these modeling goals. Demonstrating the application of these new exhibit techniques for other museums and science centers, and evaluating how visitors learn in this setting will also be performed, with the results disseminated on a national level. The Museum will collaborate with two (2) other nationally known sites in this development and evaluation of exhibit components, creation of new teacher development programs, and the development of models-related web resources.
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TEAM MEMBERS:
Douglas SmithLarry BellPaul Fontiane
The North Carolina Museum of Life & Science requests $627,003 (54.6% of a total $1,148,397 project budget) to develop "Mathematics=Easy as Pi." This will be a three-year statewide project from the North Carolina Museum of Life and Science on behalf of the 15 member museums of The North Carolina Grassroots Science Museum Collaborative to develop and implement programs and exhibits that will assist families, children and teachers to understand and appreciate mathematics. The components are a public celebration of mathematics name Pi day that will be held in 15 museums on March 14th of each year, teacher professional development workshops, 12 hands-on tabletop exhibits for 13 museums, and a Sharing math guide for use by families and children. This initiative will serve more than 2.7 million young people and adults in North Carolina over the initial three-year project. The materials will have continued usage beyond the project timeframe.
Children's Discovery Museum of San Jose, CA, will develop a three-pronged project called "Round and Round" focused on the geometry, science and technology of circles and wheels. All three project products (one permanent and one traveling version of a 2000-sq. ft. exhibition; an array of complementary educational programs for children ages 3-10; and published research on patterns of interactions among families of diverse backgrounds in museum settings) will be developed in cooperation with developmental psychologists from the University of California at Santa Cruz and advisors from Latino and Vietnamese communities in San Jose. "Round and Round" exhibits and programs will offer a trans-cultural, gender-neutral, and multi-disciplinary look at the ingenuity and ubiquity of circles. Together they will provide a comprehensive array of interactive experiences that help children, ages 3-10, and adults explore the mathematics, physics, physical properties and engineering advantages of circles and wheels. The project is expected to serve three million visitors in science and children's museums across the nation within four years of implementation.
The Educational Broadcasting Corporation (WNET, New York) is producing 14 half-hour episodes of "Cyberchase," with accompanying outreach, to extend the new animated television series into a second season. " Cyberchase," which began airing on PBS in January, 2002, engages children ages eight to eleven years old in the fun and challenge of mathematics. Its goal is to demonstrate the usefulness of mathematics and empower children to become mathematical problem-solvers by fostering a positive attitude toward mathematics, reinforcing basic mathematics concepts, modeling reasoning skills and motivating children to approach mathematics with confidence. The funds will also support the design and implementation of an outreach program, including materials for parents; a workshop activity kit for schools, libraries and museums; and ten pilot after-school programs. Specifically, outreach components include: A web component that provides mathematical activities and content for the target audience and their parents; A 12-page Cyberchase Magazine (50,000 copies); A 20-page Teacher's Guide (15,000 copies); Collector Cards (50,000 sets of six cards each); and a Poster Peer review, extensive evaluation and a national advisory board will inform all components.
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TEAM MEMBERS:
Sandra SheppardCarey BolsterMichael TempletonBarbara Flagg
The Ft. Worth Museum of Science and History will develop "Texas Dinosaurs: How Do We Know? -- Regional Dissemination of Science Inquiry Exhibits and Educational Programs on Paleontology." This will be a major permanent and portable exhibition project that will be accompanied by an array of educational programs for formal and informal audiences throughout Texas. The permanent 12,000 sq. ft. exhibit, "Texas Dinosaurs: How Do We Know?", will recreate field and laboratory processes of paleontological research in an inquiry approach to public learning in geology, biology, ecology and mathematics. Portable versions of the exhibit will be distributed to the Dinosaur Valley State Park in Glen Rose, the Texas Parks and Wildlife Headquarters, the Panhandle-Plains Historical Museum in Canyon, the Science Spectrum in Lubbock, the McAllen International Museum, and the El Paso Insights Science Museum -- all in Texas. Regional dissemination of "How Do We Know?" exhibits and educational programs and materials will reach at least 1.5 million people annually, including isolated rural communities in the large geographic region of Texas.