This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
The Nanoscale Science and Engineering Center entitled New England Nanomanufacturing Center for Enabling Tools is a partnership between Northeastern University, the University of Massachusetts Lowell, the University of New Hampshire, and Michigan State University. The NSEC unites 34 investigators from 9 departments. The NSEC is likely to impact solutions to three critical and fundamental technical problems in nanomanufacturing: (1) Control of the assembly of 3D heterogeneous systems, including the alignment, registration, and interconnection at three dimensions and with multiple functionalities, (2) Processing of nanoscale structures in a high-rate/high-volume manner, without compromising the beneficial nanoscale properties, (3) Testing the long-term reliability of nano components, and detect, remove, or prevent defects and contamination. Novel tools and processes will enable high-rate/high-volume bottom-up, precise, parallel assembly of nanoelements (such as carbon nanotubes, nanorods, and proteins) and polymer nanostructures. This Center will contribute a fundamental understanding of the interfacial behavior and forces required to assemble, detach, and transfer nanoelements, required for guided self-assembly at high rates and over large areas. The Center is expected to have broader impacts by bridging the gap between scientific research and the creation of commercial products by established and emerging industries, such as electronic, medical, and automotive. Long-standing ties with industry will also facilitate technology transfer. The Center builds on an already existing network of partnerships among industry, universities, and K-12 teachers and students to deliver the much-needed education in nanomanufacturing, including its environmental, economic, and societal implications, to the current and emerging workforce. The collaboration of a private and two public universities from two states, all within a one hour commute, will lead to a new center model, with extensive interaction and education for students, faculty, and outreach partners. The proposed partnership between NENCET and the Museum of Science (Boston) will foster in the general public the understanding that is required for the acceptance and growth of nanomanufacturing. The Center will study the societal implications of nanotechnology, including conducting environmental assessments of the impact of nanomanufacturing during process development. In addition, the Center will evaluate the economic viability in light of environmental and public health findings, and the ethical and regulatory policy issues related to developmental technology.
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TEAM MEMBERS:
Ahmed BusnainaNicol McGruerGlen MillerCarol BarryJoey Mead
The National Nanotechnology Infrastructure Network (NNIN) is a partnership of 13 institutions (Cornell University, Georgia Institute of Technology, Harvard University, Howard University, North Carolina State University (affiliate), Pennsylvania State University, Stanford University, University of California at Santa Barbara, University of Michigan, University of Minnesota, University of New Mexico, University of Texas at Austin, and University of Washington) that provides multi-faceted, interdisciplinary, and broadly-accessible infrastructure supporting both near-term and long-term needs identified in the National Nanotechnology Initiative. The partnering facilities are open laboratories providing outstanding service to the external user, comprehensive training and staff support, and support of interdisciplinary and emerging areas of research, with openness to new materials, techniques, and applications.
Cornell University, through Main Street Science (the education program of its Nanobiotechnology Center), proposes to create a 3,500 sq. ft. traveling exhibition on nanoscale science and engineering in partnership with Sciencenter of Ithaca, New York. Intellectual Merit: The exhibition will address two questions: How do we see things too small to see, and how do we make things too small to see? In sections titled Small, Smaller, Nano; Seeing Nano Structures; Making Nano Stuff; and Nano and Me, hands-on activities and experiences will present the tools, processes and applications of nanoscale science and engineering for children ages 8 to 13 and adults. Broader Impact: This traveling exhibition is projected to reach some three million visitors in at least six sites as part of its national tour. It will then become a permanent exhibition at Sciencenter. Dissemination will be supported by a web site, take-home materials, a children's book and activities to carry out at home, along with links to formal education.
Kikim Media requests $743,316 to produce four half-hour television documentaries and associated outreach programs based on Michael Pollan's best-selling book, The Botany of Desire. The project explores the reciprocal nature of people's relationship with plants. The programs focus on the connections between apples and the human desire for sweetness; tulips and the desire for beauty; marijuana and the desire for intoxication; and corn and our desire for control over nature. The project will increase public understanding of diverse subjects including genetics, evolution, cognition and biochemistry as well as biodiversity, genetic diversity and the consequences of their loss. The project will have a broad impact through a national primetime PBS broadcast, an outreach program targeting adult audiences, and an educational module delivering appropriate content (excluding intoxication) to middle and high school audiences. Knight-Williams Research Communications will conduct the evaluation for The Botany of Desire television broadcast and outreach efforts.