This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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TEAM MEMBERS:
Efi Foufoula-GeorgiouChristopher PaolaGary Parker
resourceprojectProfessional Development, Conferences, and Networks
The Nanoscale Science and Engineering Education (NSEE) Center for Learning and Teaching (NCLT) would focus on the research and development of nano-science instructional resources for grades 7-16, related professional development opportunities for 7-12 teachers, and programs infused with nano-science content for education doctoral students. The Center would bring together educators and scientists from several areas of nano-science and engineering research to collaborate with science teachers and doctoral candidates in education on both the development of the resources and research on their efficacy. The PI has prior experience as director of the Materials World Modules project, an NSF-funded curriculum currently in use in several secondary schools across the country. Lead partners in the proposed Center are Northwestern University, Purdue University, University of Michigan, University of Illinois at Chicago and University of Illinois at Urbana-Champaign. Additional partners include Argonne National Laboratory, West Point Military Academy, Alabama A & M University, Fisk University, Hampton University, Morehouse College and University of Texas at El Paso. The additional partners will widen the geographic range of the project, expanding opportunities to reach a diverse and currently underrepresented population of graduate students, teachers and ultimately students. STEM and Education faculty and researchers from the partner institutions would participate in interdisciplinary teams to address the Center's mission: Provide national education leadership and resources for advancing NSEE Create and implement professional development programs in NSEE Use innovative ideas in learning to design instructional materials for grades 7-16 Conduct research relating to integration of NSEE into science, technology, engineering and mathematics (STEM) education.
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TEAM MEMBERS:
R. P. H. ChangThomas MasonNcholas GiordanoJoseph Krajcik
Community Ambassadors in Science Exploration (CASE) is a new model for encouraging the appreciation and understanding of science among underserved families through: a corps of teen and adult peer presenters; a curriculum of hands-on learning experiences for families of diverse ages and backgrounds; a regional network of museum-community collaboration; integration of community and museum resources through joint programming; and a longitudinal research study of program impacts. CASE will serve over 20,000 people over three years with peer-presented family learning opportunities and museum experiences. In addition, CASE will train a total of 108 science ambassadors who will offer science workshops at community-based organizations in the languages spoken by their constituencies. Through CASE, the ambassadors will gain training and experience in informal science education that can open the door to possible future career opportunities in community and museum settings. Building on a ten-year history of museum-community collaboration, CASE will be conducted by PISEC, the Philadelphia/Camden Informal Science Education Collaborative. PISEC includes four major Philadelphia informal science institutions: The Franklin Institute, the Philadelphia Zoo, The Academy of Natural Sciences and The New Jersey State Aquarium. This organization conducts research and outreach projects in support of family science learning.
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TEAM MEMBERS:
Minda BorunKathleen WagnerAngela WengnerNaomi Echental
Independent Production Fund is producing a three-part public television series focusing on the latest research in the science of music. The programs will explore how cutting-edge science is revealing new connections between music and the human mind and body, the natural world and the cosmos. The series will follow researchers from a variety of fields including physiology, neuroscience, psychology, biology, physics and education, as they use groundbreaking techniques and technologies to unravel age-old mysteries about music's persistence, universality and emotional power. It will show how these researchers are shedding valuable new light on the way brains work. The impact of the programs will be extended through a content-rich companion web site and innovative formal and informal educational-outreach materials to both middle and high school age students, as well as a complementary radio component. Mannes Productions will produce the series; Goodman Research Group will conduct formative evaluation and Rockman et al will conduct summative evaluation.
Kikim Media requests $743,316 to produce four half-hour television documentaries and associated outreach programs based on Michael Pollan's best-selling book, The Botany of Desire. The project explores the reciprocal nature of people's relationship with plants. The programs focus on the connections between apples and the human desire for sweetness; tulips and the desire for beauty; marijuana and the desire for intoxication; and corn and our desire for control over nature. The project will increase public understanding of diverse subjects including genetics, evolution, cognition and biochemistry as well as biodiversity, genetic diversity and the consequences of their loss. The project will have a broad impact through a national primetime PBS broadcast, an outreach program targeting adult audiences, and an educational module delivering appropriate content (excluding intoxication) to middle and high school audiences. Knight-Williams Research Communications will conduct the evaluation for The Botany of Desire television broadcast and outreach efforts.
After-School Math PLUS (ASM+) uses the rapidly growing field of informal education as a venue to develop positive attitudes, build conceptual knowledge, and sharpen skills in mathematics for underserved youth in grades 3-8. "ASM+" brings families and children together in the pursuit of mathematics education and future career interests and directly addresses the NSF-ISE's four areas of special interests: (1) builds capacity with and among informal science education institutions; (2) encourages collaborations within communities; (3) increases the participation of underrepresented groups; and (4) models an effective after-school program. " ASM+" is being developed in collaboration with the New York Hall of Science and the St. Louis Science Center with support from after-school centers in their communities. "ASM+" incorporates the best practices of existing programs, while adding its own innovative elements that have proven successful in the NSF-funded "After-School Science Plus" (HRD #9632241). "ASM+" is aimed at underserved youth and their families, as well as after-school group leaders and teenage museum explainers who will benefit from training and participation in the project. It has facilitated the creation of alliances between museums, after-school centers, schools and the community.
Community Science Workshops: Beginning a National Movement is an extension of a successful, NSF-funded project that created a network of community science centers in California. The San Francisco State University will now take this successful venture to a national level by working with the American Association for the Advancement of Science (AAAS) and Quality Education for Minorities (QEM) to establish a new Community Science Workshop (CSW) 8-10 in underserved communities over the next four years. Once sites are selected, CSW directors participate in an intensive two-week training program. This is followed by visits by site mentors, and ongoing support through the WWW and other media, which contributes to the establishment and eventual sustainability of the centers. Each site partners with larger, established museums and science centers locally to gain much needed assistance with exhibits and education programs. Community Science Workshops contain permanent exhibit space, a workshop area for student projects and classroom/storage space. They serve a variety of audiences through after school, family, school and summer science programs. Potential locations include Arizona, Florida, Louisiana, Michigan, Montana, Nebraska, New York, Tennessee, Texas, Washington and the District of Columbia.
Mixing in Math is a multi-dimensional, three-year project that seeks to build the capacity of after-school programs to provide meaningful and engaging math activities for youth. Program collaborators including project leaders from TERC and after-school program leaders will reach approximately 40,000 children through at least 350 sites and approximately 9,000 staff and volunteers. Drawing on the unique features of the after-school environment, the project design includes the following elements: development of materials appropriate to the setting; staff development and support; institutionalization and dissemination of materials throughout an established network and evaluation research to further knowledge about informal math and after-school programming. Project goals are to: provide free math materials to all participating after-school staff; produce a significant increase in informal math training for the after-school workforce; strengthen the role of informal math in after-school settings; and conduct and disseminate research on the project in terms of its impact on after-school programming, informal math education and the math "achievement gap." "Mixing in Math" national partners will facilitate further reach of the project. The National Institute of Out of School Time (NIOST) in addition to posting materials on their website, will incorporate project activities into their staff development programs. Ceridian, a work-life benefits provider, will distribute project materials to workplace school-ages childcare programs.
The Science Museum of Minnesota (SMM) will carry out a museum-wide initiative to distribute exhibits and programs about new science and research among its core exhibits. The project goal is to redefine science for visitors as a dynamic human endeavor that is rich in discovery and relevant to their lives, as well as to position SMM as a resource for complex science and science issues. The project includes Current Science Central (500 sq ft) plus three Current Science Zones (250-300 sq ft) distributed among existing galleries (Mississippi River, Human Body, Experiment). Standardized formats (e.g., newscast scripts, quiz questions, multimedia kiosks, bulletin/graffiti boards) will provide frameworks that simplify the constant need for updating content and increase the ability to respond quickly. Target audiences are families, school groups, teachers, teens and lifelong learners from among the 850,000 annual visitors; involvement of the Youth Science Center will engage underserved audiences. Project collaborators are researchers (University of Minnesota, Augsburg College, Gentra Systems, 3M and JPL), as well as media (Physics Today, television and radio). The science museum field will benefit from the experience gained through this project.
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TEAM MEMBERS:
Liza PryorCari DwyerMark DahlagerPaul Martin
This comprehensive ITEST project would provide sixty middle and high school teachers with an introduction to Geographic Information System (GIS) and Global Positioning System (GPS) technologies. The project, which brings together a leadership team of educators, science researchers and experts in resource management, is based at the University of Maryland Center for Environmental Science Appalachian Laboratory, a research facility that studies stream and forest ecosystems. The program will focus on environmental applications in which teachers use probes to investigate the properties of local forest and stream ecosystems. Teachers will apply their technology experiences to creating standards based lessons aligned with local curricula. The teacher participants will be recruited from rural, underserved Appalachian communities in western Maryland and northern West Virginia. Local students will be recruited to participate in a four-day summer session that includes field-testing the proposed lessons and learning about career opportunities in information technology.
The Science Museum of Minnesota (SMM)--in collaboration with scientists at the University of Minnesota's Center for Infectious Disease Research and Policy and Academic Health Center; the Minnesota Department of Health, and the Minnesota Antibiotic Resistance Collaborative--requests a Phase 1/11five-year SEPA grant of $1,250,000 to develop a traveling museum exhibition and web site that highlight the fascinating science behind the outbreaks of emerging and re-emerging infectious diseases that are changing and shaping our way of life in the 21st century. Topics to be covered will include the emergence of new illnesses like SARS and Avian Influenza and the re-emergence of drug-resistant infections that were once curable but now can be fatal. An Infectious Disease Advisory Panel and Content Experts representing the collaborating institutions listed above and others will guide museum staff in the development of these exhibits and programs. EMERGING INFECTIOUS DISEASES will be a 1,500 square-foot special exhibition to be installed in SMM's Human Body Gallery in spring 2007. After an 18-month presentation, it will begin a tour to five medium size science centers over two years. In addition to the exhibition and its complementary web site, special programming will be targeted to reach specific audiences, including: K-12 school groups visiting the museum (a user guide with on-line pre- and post-visit activities aligned with state and National Science Education Standards); K-12 classroom teachers (Curriculum Enhancement Institutes); and outreach programs serving after-school programs for children in under-served inner-city neighborhoods. A focus on areas of ongoing research will be used to highlight how far we have come in understanding the complex world of infectious diseases and how far we must go in treatment or elimination of present day health threats.