This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
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TEAM MEMBERS:
Harold CraigheadBarbara Baird
resourceprojectProfessional Development, Conferences, and Networks
This MSP-Start Partnership, led by Widener University, in partnership with Bryn Mawr College, Delaware County Community College, Philadelphia University, Lincoln University, and Haverford Township School District, is developing the Greater Philadelphia Environment, Energy, and Sustainability Science (ES)2 Teacher Leader Institute. Additional partners include the Center for Social and Economic Research at West Chester University, Delaware Valley Industrial Resource Center, Energy Coordinating Agency, US EPA Region 3 Office of Innovation, National Center for Science and Civic Engagement and its SENCER program, Pennsylvania Campus Compact, Philadelphia Higher Education Network for Neighborhood Development, Project Kaleidoscope, Sustainable Business Network of Greater Philadelphia, and the 21st Century Partnership for STEM Education. Building on a base of relationships developed over the past five years by many partners in the Math Science Partnership of Greater Philadelphia, the project brings together faculty and resources from multiple institutions (a "Mega-University" model) to develop a coherent, innovative, and content-rich, multi-year curriculum in environment, energy, and sustainability science for an Institute that leads to a newly developed Master's degree. Teachers participating in the Institute (A) improve their STEM content knowledge in areas critical to human environmental sustainability, (B) improve their use of project based/service learning and scientific teaching pedagogies in their teaching, (C) engage in real-world sustainability problem solving in an externship with a local business, non-profit or government organization that is active in the newly emerging green economy, and (D) develop important leadership skills as change agents in their schools to improve student interest, learning, and engagement in STEM education. The Institute aims to serve as a regional hub, connecting educational, business, non-profit and government organizations to strengthen the STEM education and workforce development pipelines in the region and simultaneously support positive social change toward environmental sustainability and citizenship. The project's "Mega-University" and "Institute as a regional connector-hub" approaches are powerful models of collaboration that could have widespread and significant national applicability as organizations and systems adjust to the new challenges of our global economy and to the needed transition to sustainability.
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TEAM MEMBERS:
Stephen MadigoskyWilliam KeilbaughVictor DonnayBruce GrantThomas Schrand
Safe Techniques Advance Research – Laboratory Interactive Training Environment (STAR-LITE) is an innovative laboratory safety training created by the National Institutes of Health, Office of Research Services, Division of Occupational Health and Safety, for high school and undergraduate students. The training was designed to incorporate laboratory safety and risk assessment with the architecture of game-based learning. In this respect, STAR-LITE provides student users with a salient educational experience that uses visual and audio clues, strategic thinking, and physical action to enhance the learning experience. The goal of STAR-LITE is to expand the student’s knowledge base with an introduction to safe laboratory and common risk assessment techniques. STAR-LITE comprises a series of pursuit or Quest-based activities that occur in a virtual laboratory environment. Users direct individualized characters, or avatars, to interact and engage with the features in the virtual laboratory to progress through continuous challenges. STAR-LITE provides users with a significant, repeatable educational experience using visual and audio clues, strategic thinking, and physical action to enhance the learning process. This training offers a unique method of instruction by integrating development of critical thinking proficiencies and application of problem solving skills with visualization of consequences, which result from unsafe behaviors. STAR-LITE’s educational content is presented in a virtual laboratory environment in which virtual characters experience exposures to hazardous biological, chemical, and physical hazards with real-life consequences. Student users participate in a series of Quests that require interaction with characters and laboratory equipment. Basic laboratory safety skills and techniques are presented in the training. These skills and techniques include an introduction to potential biological, chemical, and physical hazards that may be present in multi-discipline laboratories; methods to prevent injuries in the laboratory; methods to protect students, colleagues, and the environment from potential hazards in the laboratory; and emergency preparedness and response basics. STAR-LITE was designed to ensure student users walk through a risk assessment process during each Quest. Because STAR-LITE is a digital game-based learning experience, users can repeat the training as many times as they like. The repeatability of this training enhances the student’s learning experience and allows them to pursue different risk assessment decision paths as they progress through the Quest.
The University of Washington’s Museology Program, in partnership with the Woodland Park Zoo and the Learning in Informal and Formal Environments Research Center is developing a model of university-community collaboration where students work with client museums, zoos and aquaria to evaluate exhibits and programs under the guidance of a research mentor. Students will gain experience in audience research and evaluation, as well as in project management, collaboration, and leadership. Staff at participating museums will advance their personal knowledge about visitors and the field of museum evaluation. The project will prepare a new generation of evaluators and museum practitioners through an innovative apprentice-styled laboratory that integrates the strengths of mentoring, fieldwork, academics, and client-centered experiences. Project Advisors include John Falk, Julie Johnson, Randi Korn, Marjorie Schwarzer, and Patterson Williams. Project started January, 2009 with 24 graduate students in the first cadre.
This research study involves collaboration between researchers at the University of Maryland, College Park and Bowie State University, an HBCU, to examine a multi-component pre-service model for preparing minority students to teach upper elementary and middle level science. The treatment consists of (1) focused recruitment efforts by the collaborating universities; (2) a pre-service science content course emphasizing inquiry and the mathematics of data management; (3) an internship in an after school program serving minority students; (4) field placements in Prince Georges County minority-serving professional development schools; and (5) mentoring support during the induction year. The research agenda will examine each aspect of the intervention using quantitative and qualitative methods and a small number of case studies.
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TEAM MEMBERS:
James McginnisSpencer BensonScott Dantley
resourceprojectProfessional Development, Conferences, and Networks
This four year project led by The American Association for the Advancement of Sciences (AAAS) will continue fostering interactions among projects funded by the Graduate STEM Fellows in K-12 Education (GK-12)through a series of meetings that include one annual meeting and two special focus meetings every year. The annual meeting will be broad and will target all different GK-12 participants (PIs, Fellows, Teachers, Project Coordinators, Evaluators and Faculty Members). The special focus meetings will target a specific GK-12 group or will explore a theme or issue of special interest to the GK-12 program or GK-12 projects. AAAS also will update the current website and revise and expand its content to provide a resource to the GK-12 community. Some of the additions to the website will be: an e-newsletter, alumni directory, evaluation instruments, ready access to STEM activities and statistical data on projects.
Evaluators sought to determine impact on math attitude and content knowledge of students (3rd - 6th grade), and math literacy workers (high school and college students), based on pre-post testing and observation of YPP after school programs, in which college and high school students teach math games to elementary and middle school students in marginalized and vulnerable communities. The study focused on the Chicago YPP site, 1 of 7 in the YPP national network. Increases in math attitude scores were not statistically significant, however in some instances evaluators found significant increases
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TEAM MEMBERS:
Norman LedermanYoung People's Project, Inc.
The Nanoscale Science and Engineering Center entitled New England Nanomanufacturing Center for Enabling Tools is a partnership between Northeastern University, the University of Massachusetts Lowell, the University of New Hampshire, and Michigan State University. The NSEC unites 34 investigators from 9 departments. The NSEC is likely to impact solutions to three critical and fundamental technical problems in nanomanufacturing: (1) Control of the assembly of 3D heterogeneous systems, including the alignment, registration, and interconnection at three dimensions and with multiple functionalities, (2) Processing of nanoscale structures in a high-rate/high-volume manner, without compromising the beneficial nanoscale properties, (3) Testing the long-term reliability of nano components, and detect, remove, or prevent defects and contamination. Novel tools and processes will enable high-rate/high-volume bottom-up, precise, parallel assembly of nanoelements (such as carbon nanotubes, nanorods, and proteins) and polymer nanostructures. This Center will contribute a fundamental understanding of the interfacial behavior and forces required to assemble, detach, and transfer nanoelements, required for guided self-assembly at high rates and over large areas. The Center is expected to have broader impacts by bridging the gap between scientific research and the creation of commercial products by established and emerging industries, such as electronic, medical, and automotive. Long-standing ties with industry will also facilitate technology transfer. The Center builds on an already existing network of partnerships among industry, universities, and K-12 teachers and students to deliver the much-needed education in nanomanufacturing, including its environmental, economic, and societal implications, to the current and emerging workforce. The collaboration of a private and two public universities from two states, all within a one hour commute, will lead to a new center model, with extensive interaction and education for students, faculty, and outreach partners. The proposed partnership between NENCET and the Museum of Science (Boston) will foster in the general public the understanding that is required for the acceptance and growth of nanomanufacturing. The Center will study the societal implications of nanotechnology, including conducting environmental assessments of the impact of nanomanufacturing during process development. In addition, the Center will evaluate the economic viability in light of environmental and public health findings, and the ethical and regulatory policy issues related to developmental technology.
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TEAM MEMBERS:
Ahmed BusnainaNicol McGruerGlen MillerCarol BarryJoey Mead
The WGBH Educational Foundation together with the Association of Computing Machinery (ACM) and dozens of partners, proposes a major new initiative to reshape the image of computing among college-bound high school students, with a special focus on Latina girls and African-American boys. Image is seen as an important factor in the lack of interest in computing majors among high school and college students, who often see computer scientists as geeks and nerds with boring jobs and equally boring lives. Latina girls and African-American boys--among the most underrepresented groups in computing--represent particularly important and challenging audiences. The New Image for Computing project will research and design a "communications make-over"--a new set of messages that will accurately and positively portray the field and will be widely tested for their emotional appeal to and intellectual connection with the targeted audiences. Experienced marketing professionals will help create the messaging campaign using proven marketing and communications strategies. WGBH, a leading producer of programming for public television and non-broadcast educational media, is uniquely positioned to lead this initiative, as they have a current, similar project called Engineer Your Life that aims to encourage academically prepared high school girls to consider engineering as an attractive option for both post-secondary education and as a career choice.
This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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TEAM MEMBERS:
Efi Foufoula-GeorgiouChristopher PaolaGary Parker
The University of Massachusetts Lowell conducted 1.5-day conference in the fall of 2011, titled "Learning on the Go: Using Out-of-Home Media to Communicate Climate Science." The conference, held at the Lowell Inn and Conference Center, brought together approximately 125 professionals and students in climate science, communications, out-of-home media, social science, informal and formal science education, and educational psychology with the goal of exploring opportunities for applying out-of-home media to communicating science to the public, with a particular emphasis on climate change science. "Out-of-home media" is defined as any type of communication that reaches individuals while they are out of the home, including mobile media, billboards, mass transit placards, posters, etc. The intent was to consider how informal science education and its impacts on learning can be expanded via the adaptation of such media to the goals of ISE. Conference proceedings and podcasts of keynote sessions will be made available on a conference Web site. Conference evaluation will be conducted by Arbor Consulting Partners.